APOE and Depression: Cognitive Consequences

 
   Lead Investigator:    Madison Lenox
   Institution      :    Nova Southeastern University
   E-Mail           :    madisonblenox@gmail.com
   Proposal ID      :    1205



   Proposal Description:
   The goals of our proposed research include exploring the APOE genotype and its relationship with cognition, subjective memory complaints, and depression in older adults. Our tentative hypothesis is that those with the presence of APOE epsilon4 allele will endorse increased memory complaints and depressive symptoms. We hope this research informs psychologists and neuropsychologists      about the importance of assessing for depression in the presence of APOE epsilon4 allele and subjective memory complaints. Further, we hope to translate the current findings to improve patient care in order to assess for and treat psychiatric disorders, specifically depression, to possibly decrease the risk     of cognitive impairment and dementias in older adults with a higher prevalence of epsilon4.